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Beyond Compliance, Adherence, & Concordance – Supporting The Patient’s Implementation Of Optimal Treatment

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The Redundant Patient Compliance Review: Helpful, Harmless, Or Hinderance?

September 29th, 2008 at 8:38 pm · · Clinical Info · 1 Comment

This One Is About Adherence to COPD Treatment

Source
Patient Adherence In COPD
Bourbeau J, Bartlett SJ.,
Thorax. 2008 Sep;63(9):831-8

The Review

First, I must point out that Patient Adherence In COPD is a well-researched, well-written, accurate review of – well, patient adherence in COPD. It is, in fact, superior to most reviews, eschewing, for example, oversimplified, easy conclusions and recognizing the limitations of the research.

I chose this specific review, in fact, to serve as context for a discussion of the inherent problems with the current concept of patient compliance because it is competently done. I want to emphasize, as I suggested in Patient Compliance Research – Finding Precisely Accurate Answers To The Wrong Question?, that the issue isn’t the quality of the research or the thoroughness of the review; the issue is whether we’re asking the right questions.

The key  points of the article follows.

The Abstract

Patient adherence to treatment in chronic obstructive pulmonary disease (COPD) is essential to optimise disease management. As with other chronic diseases, poor adherence is common and results in increased rates of morbidity, healthcare expenditures, hospitalisations and possibly mortality, as well as unnecessary escalation of therapy and reduced quality of life. Examples include overuse, underuse, and alteration of schedule and doses of medication, continued smoking and lack of exercise. Adherence is affected by patients’ perception of their disease, type of treatment or medication, the quality of patient provider communication and the social environment. Patients are more likely to adhere to treatment when they believe it will improve disease management or control, or anticipate serious consequences related to non-adherence. Providers play a critical role in helping patients understand the nature of the disease, potential benefits of treatment, addressing concerns regarding potential adverse effects and events, and encouraging patients to develop self-management skills. For clinicians, it is important to explore patients’ beliefs and concerns about the safety and benefits of the treatment, as many patients harbour unspoken fears. Complex regimens and polytherapy also contribute to suboptimal adherence. This review addresses adherence related issues in COPD, assesses current efforts to improve adherence and highlights opportunities to improve adherence for both providers and patients.

Section Headings

  • Adherence: an overview (compliance, adherence and concordance)
  • Medication and regimen factors
  • Patient factors
  • Healthcare provider and caregiver factors
  • Patient adherence in the treatment of COPD: non-adherence to medication in COPD, suboptimal adherence to non-drug therapy in COPD, strategies to enhance adherence

Excerpt From Results

Medication adherence by patients with COPD is generally poor, with reports citing adherence rates to various treatment regimens of approximately 50%. In a study of adherence in patients with COPD, 31% of patients consciously decided to forego administration of their medication if they were ‘‘feeling good.’’ In this study, forgetting or deciding not to take a dose was reported as the most frequent cause of non-adherence. Conversely, these patients reported overusing medication during periods of respiratory distress. Additional factors contributing to non-adherence included interruptions or changes in normal routines, adverse side effects, running out of medication and polypharmacy with complex dosing regimens.

Excerpt From The Conclusion

Further research is needed to gain insight into health behaviour change interventions in COPD in order to design and implement more effective self-management programmes. Such programmes offer the potential to confer clinically and cost effective strategies for long term maintenance of pharmacological and non-pharmacological treatment. Long term studies are needed to assess how successfully patients can sustain behaviour changes over time. Thus the identification and management of adherence related factors in COPD will improve not only patient health outcomes but also help improve the health status of patients and reduce the economic and societal burden associated with COPD. Trials are needed to document effects on clinically important patient outcomes, feasibility in usual practice settings and durability.

It’s The Same Old Song

I’m the first to declaim that the standard patient compliance review is not a bad song; in fact, it’s a song I like at lot. I’ve participated in the occasional standing ovation. Heck, if I were on American Bandstand, I’d give it a 99. It’s just that we’ve heard it before – 50 or 60 or a few hundred times.

The fundamental sheet music template for a patient compliance review, which correlates highly with  Patient Adherence In COPD – and dozens of others reviews and reports – calls for  the opening bars to offer an Overview Of Compliance, typically comprising a history of organized medicine’s positions on compliance, a discussion of Adherence Vs Compliance Vs Concordance, selected statistics illustrating fiscal costs, morbidity and mortality, and prevalence. Standard elements of the midsection of the piece include the impact of the treatment and the disorder under discussion on compliance, the impact of the patient’s individual psychology, culture, family, and other background on adherence, and the vital role of the healthcare provider. Specific Results often follow, highlighted by the percentage of population of patients being studied who are noncompliant. Then comes the big finish, AKA The Conclusion – familiar lyrics that go a little something like this: patient compliance must be addressed, there are no evidence-proven compliance enhancement strategies, and – here comes the final refrain – further study is needed.

I think that just about covers it. A great performance won’t get the author on the cover of Rolling Stone, but they could well win a place in a few medical journals.

The question for compliance fans is how much value is left to be garnered by more performances of the same power ballad.

Who believes the problem is that the patient compliance reviews and research aren’t exacting enough, aren’t thorough enough, aren’t insightful enough, … ?  Show of hands.  OK, no one believes that. Who believes that the next review of adherence among tuberculosis patients will reveal a clinical truth of significant importance?  No one? OK, how about that same review written about asthma patients, adolescents with acne, lepers over 60 years old, bloggers following a physical therapy regimen after a hip pinning, … ?

Here’s my point:
Even if one loves Motown (and I do), eventually one learns (and I did) that listening to Leonard Cohen, Bruce Springsteen, or Death Cab For Cutie offers qualities that just aren’t available from The Supremes or Gladys Knight and The Pips. Listening exclusively to the same Top 40 on the same Golden Oldies station is unlikely to expand ones musical horizons.

Tags: Clinical Info

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