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Beyond Compliance, Adherence, & Concordance – Supporting The Patient’s Implementation Of Optimal Treatment

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Noncompliance With HIV Treatment Among Teenaged Sexual Assault Victims

July 17th, 2006 at 5:04 am · Allan Showalter, MD · Noncompliance · No Comments




Published Article:
Use of human immunodeficiency virus postexposure prophylaxis in adolescent sexual assault victims
Olshen E, Hsu K, Woods ER, Harper M, Harnisch B, Samples CL.
Arch Pediatr Adolesc Med. 2006 Jul;160(7):674-80.

Release To Lay Press:
Teen sexual assault victims rarely finish HIV-exposure drugs
Advocate.com Reuters. July 15, 2006
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Results

The stark numbers of a study by Elyse Olshen & colleagues tell a terrifying story:

  • 145 adolescent patients (97% female) seen within 3 days of sexual assault


  • 129 were offered HIV postexposure prophylaxis


  • 110 agreed to its use


  • 86 began the protocol


  • 13 completed the full course of treatment

The authors conclude:

We agree with published recommendations that PEP be offered to adolescent sexual assault survivors for exposures that pose a risk of HIV transmission. Patient education and a comprehensive follow-up system with extensive outreach and case management are necessary to encourage PEP adherence and return for follow-up care among adolescent sexual assault survivors.

Commentary

Given the extreme degree of noncompliance and the long-term risk to these adolescents and to those with whom they come into contact, “patient education” and follow-up programs “to encourage PEP adherence” may not represent a proportionate response to the situation. It would seem that a more aggressive approach, perhaps Directly Observed Therapy, is warranted.

Tags: Noncompliance